Description

Boc-Pro-Pro-Pro-Pro-Oh is a high-purity, protected tetrapeptide building block essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over peptide chain elongation and side-chain protection strategies. It is primarily utilized in pharmaceutical R&D for the development of novel therapeutic peptides and in biochemical studies exploring protein structure and function.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of longer, complex peptide sequences in drug discovery.
• Pharmaceutical Research: Used in the development and scale-up of peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation: Serves as a building block for creating peptide tags, linkers, or carriers in antibody-drug conjugate (ADC) and diagnostic probe development.
• Biochemical Tool Development: Employed in synthesizing substrates, inhibitors, or standards for enzyme activity assays and proteomics research.
• Material Science: Potential use in creating bio-inspired polymers and peptide-based nanomaterials with specific structural properties.

Basic Information

Product Name	Boc-Pro-Pro-Pro-Pro-Oh
CAS No.	29804-52-2
Molecular Formula	C24H38N4O7
Molecular Weight	494.58 g/mol
Synonyms	Boc-Pro-Pro-Pro-Pro-OH; Boc-L-Prolyl-L-prolyl-L-prolyl-L-proline; tert-Butyloxycarbonyl-L-prolyl-L-prolyl-L-prolyl-L-proline; (2S)-1-[(2S)-1-[(2S)-1-[(2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid; Boc-Pro4-OH; Boc-(Pro)4-OH; N-α-Boc-tetrakis(L-proline)
EINECS	Contact for details

Quality Control

Our Boc-Pro-Pro-Pro-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.