Description

Proline CAS NO 29795-82-2 is a non-essential, cyclic amino acid that serves as a fundamental building block in biochemistry and industrial synthesis. Its unique pyrrolidine ring structure imparts conformational rigidity, making it a critical component for modifying peptide and protein properties. This versatile compound is essential for manufacturers and researchers in the pharmaceutical, nutraceutical, and cosmetic industries, where it is used to synthesize bioactive peptides, formulate supplements, and develop advanced skincare products.

Application

• Pharmaceutical Intermediates: A key chiral building block for the synthesis of various APIs (Active Pharmaceutical Ingredients) and complex peptide-based drugs.
• Nutraceutical & Dietary Supplements: Used in the formulation of sports nutrition, anti-aging supplements, and products aimed at supporting collagen synthesis and joint health.
• Cosmetic & Personal Care: Incorporated into skincare formulations for its moisturizing properties and its role as a precursor to collagen, helping to improve skin elasticity and texture.
• Biochemical Research & Cell Culture: Employed as a component of cell culture media and in various biochemical assays to study protein structure, enzyme function, and metabolic pathways.
• Food & Flavor Enhancement: Used as a flavor modifier and sweetener potentiator in certain food products.
• Organic Synthesis: Serves as a versatile chiral auxiliary and starting material in asymmetric synthesis for producing fine chemicals and specialty compounds.

Basic Information

Product Name	Proline
CAS No.	29795-82-2
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	L-Proline; (S)-Pyrrolidine-2-carboxylic acid; Pro; P; (-)-Proline; 2-Pyrrolidinecarboxylic acid; (S)-(-)-Proline; L-(-)-Proline; L-Azetidine-2-carboxylic acid (related structure)
EINECS	249-942-3

Quality Control

Our Proline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We offer various grades, including Pharmaceutical (USP/EP), Food (FCC), and Research grades, each meeting stringent specifications. Comprehensive testing, including chiral purity assay and residual solvent analysis, is performed. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which can affect quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]20/D	-84° to -86° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.