Description

5-Fluoro-2-Thiophenecarbaldehyde is a versatile fluorinated heterocyclic building block, essential for the synthesis of complex organic molecules. Its value lies in the strategic introduction of both a formyl group and a fluorine atom onto the thiophene scaffold, enabling precise molecular modifications. This compound is critically needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Functional Material Research: Employed in the synthesis of organic semiconductors, conductive polymers, and nonlinear optical (NLO) materials due to the electron-rich thiophene core.
• Chemical Biology Probes: Utilized to build fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis and Scale-Up: Provides a reliable starting point for contract research organizations (CROs) and fine chemical manufacturers for custom synthesis projects.

Basic Information

Product Name	5-Fluoro-2-Thiophenecarbaldehyde
CAS No.	29669-49-6
Molecular Formula	C5H3FOS
Molecular Weight	130.14 g/mol
Synonyms	5-Fluorothiophene-2-carboxaldehyde; 2-Formyl-5-fluorothiophene; 5-Fluoro-2-formylthiophene; 5-Fluorothiophene-2-carbaldehyde; 5-Fluoro-2-thiophenecarboxaldehyde; 5-Fluorothiophene-2-aldehyde; 5-Fluoro-2-thienylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Thiophenecarbaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is compatible with strong acid/organic solvent environments. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.