Description

Poly-S-Cbz-L-Cysteine Mol Wt 5000-15000 is a synthetic, protected polypeptide derivative where the cysteine thiol groups are shielded with carboxybenzyl (Cbz) protecting groups. This product is critical for advanced research and development in peptide synthesis, providing a stable intermediate that prevents unwanted disulfide bond formation during complex coupling reactions. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions working on novel therapeutic peptides, drug delivery systems, and biomaterials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the solid-phase and solution-phase synthesis of complex cysteine-containing therapeutic peptides.
• Drug Delivery Research: Utilized in the development of peptide-based drug conjugates and targeted delivery systems where controlled disulfide bridge formation is required.
• Bioconjugation Chemistry: Acts as a functional polymer scaffold for attaching drugs, probes, or other molecules via the protected thiol groups, which can be deprotected as needed.
• Biomaterial Fabrication: Used in creating hydrogels and other biomaterials that rely on thiol-mediated cross-linking for stability and functionality.
• Protecting Group Strategy: Provides a model compound for studying and optimizing Cbz protection/deprotection strategies in polypeptide chemistry.
• Reference Standard: Functions as a characterized reference material for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	Poly-S-Cbz-L-Cysteine Mol Wt 5000-15000
CAS No.	29663-62-5
Molecular Formula	(C11H11NO4S)n
Molecular Weight	5000 - 15000 (Average)
Synonyms	Poly(S-carboxybenzyl-L-cysteine); Poly(S-Cbz-L-cysteine); Poly(S-benzyloxycarbonyl-L-cysteine); PCBLC; Poly(S-Z-L-cysteine); L-Cysteine, S-[(phenylmethoxy)carbonyl]-, homopolymer; NSC 334319; Poly(S-carbobenzoxy-L-cysteine)
EINECS	Contact for details

Quality Control

Every batch of Poly-S-Cbz-L-Cysteine is produced and tested under strict quality management protocols to ensure consistency and reliability for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific purity, molecular weight distribution, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95%
Average Molecular Weight (GPC)	5000 - 15000 Da
Moisture Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.