Description

Phenylthiohydantoin Arginine is a specialized derivative of arginine, a fundamental amino acid, modified with a phenylthiohydantoin group. This compound is of significant value in biochemical research and analytical chemistry, particularly for peptide sequencing and protein analysis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers requiring high-purity reagents for advanced proteomic studies.

Application

• Peptide Sequencing Reagent: A critical reagent in the Edman degradation process for determining the amino acid sequence of peptides and proteins.
• Biochemical Research: Used in academic and industrial laboratories for studying protein structure, function, and post-translational modifications.
• Proteomics & Biomarker Discovery: Employed in advanced proteomic workflows to identify and characterize proteins in complex biological samples.
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the development of peptide-based therapeutics and biologics.
• Diagnostic Kit Manufacturing: Used in the production of high-sensitivity diagnostic assays and kits that rely on precise protein identification.
• Quality Control Standard: Acts as a reference standard in QC laboratories for validating peptide synthesis and analysis methods.

Basic Information

Item	Details
Product Name	Phenylthiohydantoin Arginine
CAS No.	29635-93-6
Molecular Formula	C15H21N5O2S
Molecular Weight	335.43 g/mol
Synonyms	PTH-Arginine; 5-(3-Amino-3-carboxypropyl)-3-phenyl-2-thiohydantoin; Arginine Phenylthiohydantoin; Arg-PTH; PTH-Arg; 2-Thio-5-[(4-amino-4-carboxybutyl)]-3-phenyl-4-imidazolidinone; N5-(diaminomethylidene)-2-[(5-oxo-3-phenyl-2-sulfanylideneimidazolidin-4-yl)methyl]-L-ornithine
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin Arginine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive analytical applications. Each lot undergoes comprehensive testing, including identification, assay, and impurity profiling via advanced chromatographic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.