Description

Monoiodotyrosine CAS NO 29592-76-5 is an iodinated derivative of the amino acid tyrosine, serving as a key biochemical intermediate. This compound is crucial for research and development in endocrinology and thyroid hormone synthesis pathways. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic institutions studying iodine metabolism and thyroid function.

Application

• Pharmaceutical Research & Development: A critical precursor and reference standard in the study of thyroid hormone biosynthesis (T3/T4) and related metabolic disorders.
• Diagnostic Reagent Manufacturing: Used in the production of calibration standards and components for immunoassays measuring thyroid function and iodine uptake.
• Biochemical Studies: Employed as a substrate or tracer in enzymatic studies and metabolic pathway analysis related to iodination processes.
• Academic & Clinical Research: Essential for investigating congenital hypothyroidism, goiter, and the effects of iodine deficiency.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control in analytical laboratories.
• Radiopharmaceutical Precursor: Acts as a starting material or non-radioactive analog in the development of radioiodinated compounds for imaging.

Basic Information

Product Name	Monoiodotyrosine
CAS No.	29592-76-5
Molecular Formula	C9H10INO3
Molecular Weight	307.09 g/mol
Synonyms	3-Iodo-L-tyrosine; L-3-Iodotyrosine; MIT; (2S)-2-Amino-3-(4-hydroxy-3-iodophenyl)propanoic acid; Iodotyrosine; 3-Iodotyrosine; 4-Hydroxy-3-iodo-L-phenylalanine; 3-Iodo-4-hydroxyphenylalanine
EINECS	249-739-8

Quality Control

Our Monoiodotyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and MS. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, detailing all test results against established specifications. Our quality commitment ensures material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-4.5° to -6.5° (c=1 in 1N HCl)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.