Description

4-Chloro-2,6-Diphenylpyrimidine is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, where the chloro group offers a reactive site for cross-coupling and nucleophilic substitution, while the diphenylpyrimidine scaffold provides a rigid, aromatic structure. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Ligand and Catalyst Development: Employed to create novel ligands for transition metal catalysis due to its nitrogen-donor capability and structural tunability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, specialized heterocyclic intermediates.

Basic Information

Product Name	4-Chloro-2,6-Diphenylpyrimidine
CAS No.	29509-91-9
Molecular Formula	C16H11ClN2
Molecular Weight	266.72 g/mol
Synonyms	2,6-Diphenyl-4-chloropyrimidine; 4-Chloro-2,6-diphenylpyrimidine; 4-Chloro-2,6-diphenyl-1,3-diazine; Pyrimidine, 4-chloro-2,6-diphenyl-; 29509-91-9; 4-Chloro-2,6-diphenyl-pyrimidine; 4-Chloro-2,6-di(phenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,6-Diphenylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.