Description

Poly(Glu, Glu-Oet) CAS NO 29323-51-1 is a synthetic polypeptide derivative of glutamic acid, specifically a copolymer of glutamic acid and its ethyl ester. This engineered polymer is valued for its unique combination of biocompatibility, controlled biodegradability, and tunable physicochemical properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biomedical, and specialty materials sectors for advanced applications requiring precise polymeric architectures.

Application

• Drug Delivery Systems: As a biodegradable carrier for controlled and targeted release of active pharmaceutical ingredients (APIs).
• Tissue Engineering Scaffolds: Serving as a biocompatible matrix to support cell growth and tissue regeneration.
• Biomedical Research: A model polymer for studying polypeptide behavior, self-assembly, and interactions in biological systems.
• Specialty Coatings & Films: Used to create functional, biocompatible surfaces for medical devices or sensors.
• Cosmetic & Personal Care Formulations: As a film-forming or conditioning agent in high-performance skincare products.
• Adhesive & Sealant Development: Explored for creating bio-based adhesives with specific bonding and degradation profiles.

Basic Information

Product Name	Poly(Glu, Glu-Oet)
CAS No.	29323-51-1
Molecular Formula	(C7H11NO4 · C5H7NO4)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(glutamic acid-co-ethyl glutamate); Poly(GA-co-EG); Glutamic Acid/Ethyl Glutamate Copolymer; Poly(Glu-co-Glu(OEt)); Poly(γ-glutamic acid-co-γ-ethyl glutamate); PGA-co-PGEG; Ethyl Glutamate-Glutamic Acid Copolymer; Poly(α-glutamic acid-co-α-ethyl glutamate)
EINECS	Contact for details

Quality Control

Our Poly(Glu, Glu-Oet) is produced under a strict quality management system. Each batch undergoes comprehensive analysis to ensure consistency in molecular weight distribution, composition ratio, and purity. Certificates of Analysis (COA) detailing parameters such as assay, residual solvents, and endotoxin levels (where applicable) are provided to support research and GMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. For long-term storage, consider desiccation or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Composition Ratio (Glu:Glu-OEt)	As per customer requirement
Weight-Average Molecular Weight (Mw)	Specified range (e.g., 10k-200k Da)
Polydispersity Index (PDI)	≤ 2.0 (Typical)
Assay (by NMR or HPLC)	≥ 95%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 5.0%
Endotoxin (for biomedical grade)	< 0.25 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.