Description

n-(5-Oxo-L-Prolyl)-L-Glutamic Acid is a high-purity, non-proteinogenic dipeptide derivative of L-glutamic acid and L-pyroglutamic acid. This compound is valued for its role as a key synthetic intermediate and building block in advanced pharmaceutical and biochemical research. It is primarily sought by manufacturers and R&D laboratories in the pharmaceutical, peptide synthesis, and life science sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce specific glutamyl and pyroglutamyl functionalities.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway research.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Nutraceutical Precursor: Investigated for use in the development of specialized nutraceuticals and bioactive compounds.

Basic Information

Product Name	n-(5-Oxo-L-Prolyl)-L-Glutamic Acid
CAS No.	29227-92-7
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	L-Glutamic acid, N-(5-oxo-L-prolyl)-; N-(5-Oxo-L-prolyl)-L-glutamic acid; N-Pyroglutamyl-L-glutamic acid; Pyroglutamylglutamic acid; PGlu-Glu; pGlu-Glu; L-Pyroglutamyl-L-glutamic acid; NSC 334855
EINECS	Contact for details

Quality Control

Our n-(5-Oxo-L-Prolyl)-L-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards suitable for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.