Description

n-(1-Deoxy-D-Fructose-1-Yl)-L-Proline is a specific fructosamine derivative formed by the Maillard reaction between L-proline and D-fructose. This compound is of significant interest in biochemical and pharmaceutical research, particularly in the study of advanced glycation end-products (AGEs) and their biological implications. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences, nutraceutical, and diagnostic reagent sectors.

Application

• Biochemical Research Standard: Used as a high-purity reference material for studying non-enzymatic glycation, protein modification, and the Maillard reaction pathway.
• Diagnostic Reagent Development: Acts as a key intermediate or calibrant in the development of diagnostic assays for measuring glycated proteins and AGEs in clinical samples.
• Pharmaceutical Intermediate: Serves as a building block or precursor in the synthesis of more complex molecules for therapeutic research targeting metabolic disorders.
• Nutraceutical & Food Science Research: Employed in studies investigating the formation and effects of dietary AGEs, supporting product development and safety assessments.
• Analytical Method Validation: Essential for developing and validating analytical methods such as HPLC, LC-MS, or ELISA for the detection and quantification of fructosamine derivatives.

Basic Information

Product Name	n-(1-Deoxy-D-Fructose-1-Yl)-L-Proline
CAS No.	29118-61-4
Molecular Formula	C11H19NO7
Molecular Weight	277.27 g/mol
Synonyms	1-Deoxy-1-(L-prolino)-D-fructose; Fructosyl-L-proline; L-Proline, N-(1-deoxy-D-fructos-1-yl)-; N-(1-Deoxyfructos-1-yl)-L-proline; Amadori compound of L-proline and D-fructose; Fructosamine derivative; Proline fructosamine; N-Fructosylproline
EINECS	Contact for details

Quality Control

Our n-(1-Deoxy-D-Fructose-1-Yl)-L-Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and specific impurity profiling to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.