Description

4-Oxo-3,4-Dihydroquinazoline-2-Carboxylic Acid is a high-value heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its significance lies in its versatile quinazoline core, which is a privileged scaffold in medicinal chemistry for designing bioactive molecules. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel therapeutic agents and high-performance materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinazoline-based drug candidates, including kinase inhibitors and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides that leverage the quinazoline pharmacophore.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and organic electronic materials.
• Academic & Industrial R&D: A valuable reagent for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex target molecules.

Basic Information

Product Name	4-Oxo-3,4-Dihydroquinazoline-2-Carboxylic Acid
CAS No.	29113-34-6
Molecular Formula	C9H6N2O3
Molecular Weight	190.16 g/mol
Synonyms	2-Quinazolinecarboxylic acid, 3,4-dihydro-4-oxo-; Quinazoline-2-carboxylic acid, 4-oxo-3,4-dihydro-; 4-Oxo-1,4-dihydroquinazoline-2-carboxylic acid; 2-Carboxy-4(3H)-quinazolinone; 4(3H)-Quinazolinone-2-carboxylic acid; 4-Oxo-3,4-dihydro-2-quinazolinecarboxylic acid; 29113-34-6
EINECS	Contact for details

Quality Control

Our 4-Oxo-3,4-Dihydroquinazoline-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.