Description

1-Methyl-4-Phenyl-1H-2,3-Benzodiazepine is a specialized benzodiazepine derivative, a class of compounds renowned for their significant biological and chemical activity. This high-purity intermediate is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of novel therapeutic agents. It is primarily sought by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the development of central nervous system (CNS) drugs and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used as a reference standard or precursor in the study of GABAA receptor modulators and CNS drug discovery.
• Fine Chemical Synthesis: Serves as a versatile intermediate for constructing complex heterocyclic compounds in medicinal chemistry.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Reference Standard: Utilized in analytical laboratories for method development, validation, and quality control of related substances.

Basic Information

Product Name	1-Methyl-4-Phenyl-1H-2,3-Benzodiazepine
CAS No.	29100-33-2
Molecular Formula	C16H14N2
Molecular Weight	234.30 g/mol
Synonyms	4-Phenyl-1-methyl-1H-2,3-benzodiazepine; 1-Methyl-4-phenyl-2,3-benzodiazepine; GYKI-52466; GYKI 52466; 1-Methyl-4-phenyl-1H-[1]benzopyrano[4,3-c]pyrazole (related structure); 29100-33-2; 1-Methyl-4-phenyl-1H-benzo[d][1,2]diazepine
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-Phenyl-1H-2,3-Benzodiazepine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.