Description

L(+)-Allo-Threonine is a non-proteinogenic stereoisomer of the essential amino acid threonine, distinguished by its unique configuration. This high-purity chiral building block is critical for advanced pharmaceutical synthesis and biochemical research where stereochemical control is paramount. It serves as a key intermediate for the development of novel therapeutics, peptide-based drugs, and specialized nutritional formulations, meeting the stringent demands of the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for antibiotics and antiviral drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate specific stereochemistry into therapeutic peptides and peptide hormones.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway analysis, and as a component in defined cell culture media.
• Nutritional Science: Employed in research for developing specialized amino acid formulations and studying amino acid metabolism and transport.
• Fine Chemical Production: Acts as a starting material or intermediate in the synthesis of complex organic molecules, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	L(+)-Allo-Threonine
CAS No.	28954-12-3
Molecular Formula	C4H9NO3
Molecular Weight	119.12 g/mol
Synonyms	(2S,3R)-2-Amino-3-hydroxybutanoic acid; allo-L-Threonine; (2S,3R)-Threonine; L-allo-Threonine; (S*,R*)-β-Hydroxy-DL-norvaline; H-allo-Thr-OH; (2S,3R)-2-Amino-3-hydroxybutyric acid
EINECS	249-322-1

Quality Control

Our L(+)-Allo-Threonine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting standards for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]20/D	+28.0° to +30.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% (L-allo isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.