Description

Hydroxylysine is a vital hydroxylated derivative of the essential amino acid lysine, playing a critical structural and functional role in collagen biosynthesis and protein modification. Its importance lies in its function as a key post-translational modification site for O-glycosylation, which is essential for tissue stability and cellular signaling pathways. This compound is primarily needed by research institutions, pharmaceutical developers, and manufacturers in the nutraceutical and biochemical synthesis sectors for advanced metabolic studies and the production of specialized peptides.

Application

• Biochemical Research & Reference Standard: Used as a high-purity standard in analytical methods (HPLC, MS) for studying collagen metabolism, lysine hydroxylation, and related enzymatic pathways.
• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic peptides and enzyme inhibitors targeting connective tissue disorders.
• Nutraceutical Formulation: Incorporated into advanced dietary supplements and clinical nutrition products aimed at supporting collagen synthesis and connective tissue health.
• Cell Culture & Microbiology: Employed in specialized cell culture media formulations to study the effects of hydroxylated amino acids on cell growth, differentiation, and extracellular matrix production.
• Diagnostic Reagent Development: Utilized in the development of assay kits and reagents for the detection and quantification of collagen degradation markers in clinical samples.

Basic Information

Product Name	Hydroxylysine
CAS No.	28902-93-4
Molecular Formula	C6H14N2O3
Molecular Weight	162.19 g/mol
Synonyms	5-Hydroxy-L-lysine; Hyl; (2S,5R)-2,6-Diamino-5-hydroxyhexanoic acid; L-Hydroxylysine; 5-Hydroxylysine; (+)-5-Hydroxy-L-lysine; (S)-2,6-Diamino-5-hydroxycaproic acid
EINECS	249-292-5

Quality Control

Our Hydroxylysine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and safety data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: +14.5° to +16.5° (c=1 in H₂O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.