Description

Z-Ala-Ome CAS NO 28819-05-8 is a protected amino acid derivative, specifically the benzyloxycarbonyl (Z)-protected form of alanine methyl ester. This compound serves as a crucial building block in peptide synthesis, offering a reactive carboxyl group and an amine protected from unwanted side reactions. It is primarily needed by pharmaceutical researchers and fine chemical manufacturers involved in developing novel peptides and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key monomer for the controlled, sequential addition of alanine residues.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing peptide chains.
• Pharmaceutical Intermediate: In the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: For introducing alanine motifs or functional handles into larger biomolecules.
• Chemical Biology Research: As a tool compound for studying enzyme-substrate interactions or metabolic pathways.
• Academic & Industrial R&D: For creating custom peptides, peptidomimetics, and other complex organic structures.

Basic Information

Product Name	Z-Ala-Ome
CAS No.	28819-05-8
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	N-Cbz-L-alanine methyl ester; N-Carbobenzoxy-L-alanine methyl ester; (S)-Methyl 2-((benzyloxy)carbonylamino)propanoate; Z-L-Ala-OMe; Cbz-L-Ala-OMe; Benzyloxycarbonyl-L-alanine methyl ester; N-Benzyloxycarbonyl-L-alanine methyl ester; L-Alanine, N-[(phenylmethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Z-Ala-Ome is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	-15.0° to -18.0° (c=1 in methanol)
Melting Point	82°C - 86°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.