Description

Boc-Ala-Gly-Oh is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel therapeutic peptide candidates.
• Solid-Phase Peptide Synthesis (SPPS): Used in automated and manual peptide synthesizers to incorporate the Alanine-Glycine sequence with N-terminal Boc protection.
• Bioconjugation: Serves as a spacer or linker molecule in the development of peptide-protein conjugates or peptide-drug conjugates (PDCs).
• Biochemical Research: Employed in studying enzyme-substrate interactions, peptide folding, and structure-activity relationships (SAR).
• Custom Peptide Service: A fundamental reagent for contract research organizations (CROs) and CDMOs offering custom peptide manufacturing.
• Proteomics: Can be used in the synthesis of standardized peptides for mass spectrometry calibration and quantification.

Basic Information

Item	Details
Product Name	Boc-Ala-Gly-Oh
CAS No.	28782-78-7
Molecular Formula	C10H18N2O5
Molecular Weight	246.26 g/mol
Synonyms	Boc-Ala-Gly-OH; Boc-L-Ala-Gly-OH; N-(tert-Butoxycarbonyl)-L-alanylglycine; N-Boc-L-alanylglycine; (2S)-2-[[(2-[(tert-butoxy)carbonyl]amino]propanoyl]amino]acetic acid; Boc-L-Ala-Gly; BOC-AG-OH; tert-Butyloxycarbonylalanylglycine
EINECS	Contact for details

Quality Control

Our Boc-Ala-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	-40.0° to -44.0° (c=1 in AcOH)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.