Description

7-Chloro-5-(1-Chlorocyclohexyl)-1,3-Dihydro-1-Methyl-2H-1,4-Benzodiazepin-2-One is a high-purity benzodiazepine derivative, a critical building block in advanced pharmaceutical research and development. This compound is valued for its precise chemical structure, which serves as a key intermediate in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Employed in the early-stage development and optimization of candidate drug molecules for neurological and psychiatric disorders.
• Chemical Synthesis: Utilized in academic and industrial research for exploring new synthetic pathways and heterocyclic chemistry.

Basic Information

Product Name	7-Chloro-5-(1-Chlorocyclohexyl)-1,3-Dihydro-1-Methyl-2H-1,4-Benzodiazepin-2-One
CAS No.	28781-62-6
Molecular Formula	C16H18Cl2N2O
Molecular Weight	325.23 g/mol
Synonyms	7-Chloro-5-(1-chlorocyclohexyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1,4-Benzodiazepin-2-one, 7-chloro-5-(1-chlorocyclohexyl)-1,3-dihydro-1-methyl-; 5-(1-Chlorocyclohexyl)-7-chloro-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Chloro-5-(1-chlorocyclohexyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1-Methyl-7-chloro-5-(1-chlorocyclohexyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 7-Chloro-5-(1-Chlorocyclohexyl)-1,3-Dihydro-1-Methyl-2H-1,4-Benzodiazepin-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.