Description

S-(2-Hydroxyethyl)Glutathione is a chemically modified derivative of the essential tripeptide glutathione, featuring a 2-hydroxyethyl group attached to the sulfur atom. This structural modification enhances its stability and alters its redox properties, making it a valuable biochemical tool and a potential precursor in advanced research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical sectors. This compound is critical for studies involving oxidative stress, enzyme mechanisms, and the development of novel therapeutic or diagnostic agents.

Application

• Biochemical Research: Used as a stable, modified substrate or inhibitor in enzymatic studies, particularly those involving glutathione S-transferases (GSTs) and other redox-related enzymes.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of prodrugs, antioxidants, and detoxification agents targeting cellular oxidative stress pathways.
• Diagnostic Reagent Formulation: Employed in the development of assay kits and diagnostic tools for measuring glutathione-related metabolic activity or oxidative status in biological samples.
• Nutraceutical & Cosmetic Science: Investigated for its potential application in advanced skincare formulations and dietary supplements designed to support cellular defense mechanisms.
• Cell Culture & Biotechnology: Applied in specialized cell culture media to modulate the intracellular redox environment for optimized protein expression or cell viability studies.

Basic Information

Product Name	S-(2-Hydroxyethyl)Glutathione
CAS No.	28747-20-8
Molecular Formula	C12H20N3O7S
Molecular Weight	350.37 g/mol
Synonyms	2-Hydroxyethylglutathione; S-(2-Hydroxyethyl)-L-glutathione; γ-Glutamyl-S-(2-hydroxyethyl)cysteinylglycine; Glutathione S-(2-hydroxyethyl) ester; NSC 113939; L-Glutathione, S-(2-hydroxyethyl)-; S-2-Hydroxyethyl glutathione
EINECS	Contact for details

Quality Control

Our S-(2-Hydroxyethyl)Glutathione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere. Keep container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.