Description

7-[(Dimethylamino)Methyl]-3,4-Dihydropyrrolo[1,2,3-Ef]-1,5-Benzodiazepin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the benzodiazepine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for CNS-targeting drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Employed in the early-stage development of potential anxiolytic, sedative, or other neuropsychiatric therapeutics.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and drug-receptor interactions.
• Process Chemistry: Acts as a starting material or intermediate in scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Item	Details
Product Name	7-[(Dimethylamino)Methyl]-3,4-Dihydropyrrolo[1,2,3-Ef]-1,5-Benzodiazepin-2(1H)-One
CAS No.	28740-81-0
Molecular Formula	C14H17N3O
Molecular Weight	243.31 g/mol
Synonyms	7-[(Dimethylamino)methyl]-1,2,3,4-tetrahydropyrrolo[1,2,3-ef][1,5]benzodiazepin-2-one; 7-(Dimethylaminomethyl)-3,4-dihydro-1H-pyrrolo[1,2,3-ef][1,5]benzodiazepin-2-one; 28740-81-0; Pyrrolobenzodiazepine derivative; Dihydropyrrolobenzodiazepinone
EINECS	Contact for details

Quality Control

Our 7-[(Dimethylamino)Methyl]-3,4-Dihydropyrrolo[1,2,3-Ef]-1,5-Benzodiazepin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) with batch-specific data is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.