Description

4-Chloro-2-Quinazolone is a versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound serves as a key intermediate for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various quinazoline-based drug candidates, including kinase inhibitors and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating novel organic electronic materials and functional polymers.
• Dye and Pigment Chemistry: Acts as an intermediate in the production of specialized heterocyclic dyes and colorants.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the discovery of new chemical entities.
• Custom Synthesis: A starting material for the contract manufacturing of complex, customer-specific organic molecules.

Basic Information

Product Name	4-Chloro-2-Quinazolone
CAS No.	28735-09-3
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	4-Chloro-2(1H)-quinazolinone; 4-Chloro-1H-quinazolin-2-one; 4-Chloroquinazolin-2(1H)-one; 2-Quinazolinone, 4-chloro-; 4-Chloro-2-quinazolinol; 4-Chloro-2-hydroxyquinazoline; NSC 163063; 4-Chloroquinazolone
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Quinazolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.