Description

Z-Gly-Gly-Leu-Nh2 is a protected tetrapeptide derivative, specifically a benzyloxycarbonyl (Z)-protected peptide amide. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of longer, more complex peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs targeting various diseases.
• Bioconjugation: Acts as a precursor for creating peptide-protein or peptide-small molecule conjugates for diagnostic and therapeutic applications.
• Biochemical Tool Development: Employed in the synthesis of enzyme substrates, inhibitors, or affinity ligands for proteomics and enzymology studies.
• Academic Research: A fundamental reagent in university and institutional labs for studying peptide structure, function, and metabolism.

Basic Information

Product Name	Z-Gly-Gly-Leu-Nh2
CAS No.	28709-62-8
Molecular Formula	C₁₉H₂₈N₄O₅
Molecular Weight	392.45 g/mol
Synonyms	N-Benzyloxycarbonyl-glycyl-glycyl-L-leucinamide; Z-Gly-Gly-L-Leu-NH₂; Cbz-Gly-Gly-Leu-NH₂; Benzyl N-[2-[[2-[(2S)-2-amino-4-methyl-1-oxopentyl]amino]-2-oxoethyl]amino]-2-oxoethyl]carbamate; N-Carbobenzoxy-glycyl-glycyl-L-leucinamide; Glycine, N-[(benzyloxy)carbonyl]glycyl-L-leucyl-, amide; Z-Gly-Gly-Leu-Amid
EINECS	Contact for details

Quality Control

Our Z-Gly-Gly-Leu-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications to ensure the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.