Description

H-Leu-Gly-Nh2 Hbr CAS NO 28671-28-5 is a high-purity, protected dipeptide derivative, specifically the hydrobromide salt of the leucine-glycine amide. This compound serves as a critical building block (amino acid derivative) in advanced organic synthesis and pharmaceutical research. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for developing novel peptide-based therapeutics and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of complex peptide drugs and peptidomimetics.
• Biochemical Research: Used as a substrate or standard in enzymatic studies and metabolic pathway investigations.
• Proteomics & Peptide Library Construction: Essential for creating custom peptide sequences for screening and diagnostic assay development.
• Cosmetic Peptide Synthesis: Employed in the production of specialized bioactive peptides for advanced skincare formulations.
• Academic Research: Serves as a fundamental reagent in university and institutional labs for organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	H-Leu-Gly-Nh2 Hbr
CAS No.	28671-28-5
Molecular Formula	C8H18N3O2 • HBr
Molecular Weight	268.16 g/mol (free base: 188.25 g/mol)
Synonyms	L-Leucyl-glycinamide hydrobromide; Glycinamide, N-L-leucyl-, hydrobromide; Leu-Gly-NH2•HBr; H-Leu-Gly-NH2•HBr; N-(L-Leucyl)glycinamide hydrobromide; Leucine-glycine amide HBr salt; Boc-Leu-Gly-NH2 deprotected salt; (S)-2-Amino-4-methyl-N-(2-amino-2-oxoethyl)pentanamide hydrobromide
EINECS	Contact for details

Quality Control

Our H-Leu-Gly-Nh2 Hbr is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.