Description

Cinoxacin CAS NO 28657-80-9 is a synthetic quinolone carboxylic acid derivative with potent antibacterial activity. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents, valued for its specific mechanism of action against gram-negative bacteria. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of antimicrobial drugs and novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of quinolone-based antibacterial agents and related active pharmaceutical ingredients (APIs).
• Antimicrobial Research: Used in biochemical and microbiological research to study bacterial DNA gyrase inhibition and mechanisms of antibiotic resistance.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Veterinary Medicine Development: Employed in R&D for creating antibacterial treatments for veterinary applications.
• Chemical Synthesis: Utilized as a specialized synthon for constructing more complex heterocyclic compounds in medicinal chemistry.

Basic Information

Product Name	Cinoxacin
CAS No.	28657-80-9
Molecular Formula	C12H10N2O5
Molecular Weight	262.22 g/mol
Synonyms	1-Ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid; Cinoxacinum; Cinoxacino; Cinoxacine; Cinoxacino [INN-Spanish]; Cinoxacinum [INN-Latin]; Abbott 40731; PD 107779; U-31920; 1-Ethyl-6,7-methylenedioxy-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid
EINECS	249-144-8

Quality Control

Our Cinoxacin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is subjected to comprehensive analytical testing, including HPLC for assay and related substances, in compliance with in-house specifications developed for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.