Description

n-Diaziridin-1-Ylphosphoryl-2,6-Dimethyl-5-[(4-Propan-2-Yloxyphenyl)Methyl]Pyrimidin-4-Amine is a specialized organophosphorus compound featuring a diaziridinyl phosphoryl group integrated with a substituted pyrimidine core. This unique structure makes it a valuable high-purity chemical intermediate for advanced research and synthesis. It is primarily sought after by pharmaceutical R&D and agrochemical development teams for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides due to its bioactive pyrimidine-phosphorus scaffold.
• Chemical Biology Probe: Serves as a precursor for photoaffinity labeling agents, leveraging the reactive diaziridine group for studying biomolecular interactions.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating specialty polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: Employed in exploratory organic synthesis to develop new methodologies and complex molecular architectures.

Basic Information

Item	Details
Product Name	n-Diaziridin-1-Ylphosphoryl-2,6-Dimethyl-5-[(4-Propan-2-Yloxyphenyl)Methyl]Pyrimidin-4-Amine
CAS No.	28536-30-3
Molecular Formula	C₁₈H₂₆N₅O₂P
Molecular Weight	375.41 g/mol
Synonyms	5-[(4-Isopropoxyphenyl)methyl]-2,6-dimethyl-N-(diaziridin-1-ylphosphoryl)pyrimidin-4-amine; Diaziridinylphosphoryl Pyrimidine Amine Derivative; 28536-30-3; 2,6-Dimethyl-5-[(4-propan-2-yloxyphenyl)methyl]pyrimidin-4-yl-diaziridin-1-ylphosphinic amide; Isopropoxy Phenyl Methyl Pyrimidine Diaziridinyl Phosphoramidate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), identity (IR, NMR), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.