Description

Ac-Leu-Nh2 CAS NO 28529-34-2 is a protected amino acid derivative, specifically the acetylated amide of L-leucine. This compound serves as a crucial high-purity building block in organic synthesis and peptide chemistry, offering controlled reactivity for the construction of complex molecules. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of peptide-based therapeutics, diagnostic agents, and advanced biomaterials.

Application

• Peptide Synthesis: As a key intermediate for the solid-phase and solution-phase synthesis of novel peptides and peptidomimetics.
• Pharmaceutical Research: Used in the discovery and development of active pharmaceutical ingredients (APIs) targeting metabolic and neurological disorders.
• Bioconjugation: Serves as a spacer or linker molecule in the design of antibody-drug conjugates (ADCs) and other bioconjugates.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and proteomics research.
• Fine Chemical Production: Acts as a chiral synthon for the asymmetric synthesis of more complex organic compounds.
• Material Science: Investigated for incorporation into specialized polymers and hydrogels with tailored properties.

Basic Information

Product Name	Ac-Leu-Nh2
CAS No.	28529-34-2
Molecular Formula	C8H16N2O2
Molecular Weight	172.23 g/mol
Synonyms	N-Acetyl-L-leucinamide; Ac-L-Leu-NH2; L-Leucine, N-acetyl-, amide; N-Acetylleucine amide; Nα-Acetyl-L-leucinamide; Ac-Leu-NH2; (S)-2-Acetamido-4-methylpentanamide; N-Acetyl-L-leucine amide
EINECS	Contact for details

Quality Control

Our Ac-Leu-Nh2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the exacting standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.