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n-(1-Adamantylcarbonyl)-Gly-L-Leu-L-Tyr-Ome CAS NO 28415-42-1
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CAS No.:28415-42-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-(1-Adamantylcarbonyl)-Gly-L-Leu-L-Tyr-OMe is a synthetic, protected tripeptide derivative featuring a unique adamantane-based moiety. This compound is valued for its role as a key intermediate in advanced peptide synthesis and pharmaceutical research, offering a stable scaffold for developing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and diagnostic agents.
Application
- Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
- Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
- Peptide Library Construction: Employed in combinatorial chemistry and solid-phase peptide synthesis (SPPS) for creating diverse peptide libraries for screening.
- Protease Inhibitor Development: Acts as a core structure for designing and optimizing novel inhibitors targeting specific proteases.
- Academic Research: Utilized in universities and research labs for studying peptide conformation, stability, and receptor-ligand interactions.
- Diagnostic Agent Synthesis: A potential precursor in the development of labeled peptides for imaging and diagnostic applications.
Basic Information
| Product Name | n-(1-Adamantylcarbonyl)-Gly-L-Leu-L-Tyr-OMe |
| CAS No. | 28415-42-1 |
| Molecular Formula | C31H45N3O6 |
| Molecular Weight | 555.71 g/mol |
| Synonyms | Admantane-1-carbonyl-Gly-Leu-Tyr-OMe; N-[(1-Adamantyl)carbonyl]glycyl-L-leucyl-L-tyrosine methyl ester; Glycyl-L-leucyl-L-tyrosine, N-[(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)]-, methyl ester; Adamantylcarbonyl-Gly-Leu-Tyr-O-methyl ester; (S)-Methyl 2-((S)-2-((2-((adamantane-1-carbonyl)amino)acetamido)-4-methylpentanamido)-3-(4-hydroxyphenyl)propanoate; AGLY-OMe; Protected AGLY Tripeptide |
| EINECS | Contact for details |
Quality Control
Our n-(1-Adamantylcarbonyl)-Gly-L-Leu-L-Tyr-OMe is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference |
| Purity (HPLC) | ≥ 95.0% |
| Specific Rotation | Contact for details |
| Water Content (KF) | ≤ 5.0% |
| Heavy Metals | < 20 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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