Description

Pyrimido[5,4-D]Pyrimidin-4-Ol (8Ci) CAS NO 28285-65-6 is a high-purity, fused heterocyclic compound belonging to the pyrimidopyrimidine class, serving as a critical advanced intermediate in pharmaceutical research and development. Its unique bicyclic structure makes it a valuable scaffold for synthesizing novel therapeutic agents, particularly in oncology and antiviral drug discovery programs. This compound is essential for medicinal chemists and R&D departments in pharmaceutical, biotechnology, and fine chemical industries seeking to develop new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting various disease pathways.
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapies due to its privileged scaffold.
• Antiviral Agent Development: Serves as a core structure for creating compounds with potential activity against viral enzymes.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead molecules.
• Biochemical Research: Used as a reference standard or probe in enzymatic assays and biochemical screening.
• Fine Chemical Synthesis: An important intermediate for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Pyrimido[5,4-D]Pyrimidin-4-Ol (8Ci)
CAS No.	28285-65-6
Molecular Formula	C6H4N4O
Molecular Weight	148.12 g/mol
Synonyms	4-Hydroxypyrimido[5,4-d]pyrimidine; Pyrimido[5,4-d]pyrimidin-4-ol; 4(3H)-Pyrimido[5,4-d]pyrimidinone; 1H-Pyrimido[5,4-d]pyrimidin-4-one; 28285-65-6; Pyrimido[5,4-d]pyrimidin-4(3H)-one; 4-Pyrimido[5,4-d]pyrimidinol
EINECS	Contact for details

Quality Control

Our Pyrimido[5,4-D]Pyrimidin-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research or cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.