Description

Dansyl-L-Cysteic Acid CAS NO 28223-61-2 is a high-purity, fluorescent-labeled derivative of cysteic acid, featuring the dansyl chromophore. This compound is critical for advanced analytical and biochemical research, offering excellent sensitivity and specificity for detection and quantification. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for protein sequencing, amino acid analysis, and as a fluorescent probe or tracer in chromatographic and electrophoretic applications.

Application

• Protein Sequencing & Peptide Mapping: Used as a fluorescent tag for N-terminal amino acid analysis in Edman degradation and related techniques.
• High-Performance Liquid Chromatography (HPLC): Serves as a derivatization agent for the sensitive detection and quantification of amino acids, particularly cysteine and cystine, via fluorescence.
• Biomarker Research: Employed in the study of oxidative stress and protein damage by labeling and detecting sulfonic acid derivatives.
• Fluorescent Probe Development: Acts as a key intermediate or reference standard in synthesizing fluorescent probes for enzymatic assays and cellular imaging.
• Capillary Electrophoresis (CE): Utilized for labeling analytes to enhance detection limits in CE and CE-MS applications.
• Reference Standard: Provides a certified standard for method validation, calibration, and quality control in analytical laboratories.
• Bioconjugation & Linker Chemistry: Functions as a reactive intermediate for attaching fluorescent labels to biomolecules like proteins and peptides.

Basic Information

Product Name	Dansyl-L-Cysteic Acid
CAS No.	28223-61-2
Molecular Formula	C15H16N2O6S2
Molecular Weight	384.43 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonyl-L-cysteic acid; L-Cysteic acid dansyl derivative; Dansyl-L-cysteine sulfonic acid; DNS-Cysteic acid; N-Dansyl-L-cysteic acid; 1-Dimethylaminonaphthalene-5-sulfonyl-L-cysteic acid; (2R)-2-Amino-3-[(5-dimethylaminonaphthalen-1-yl)sulfonylamino]-3-oxopropanoic acid
EINECS	Contact for details

Quality Control

Our Dansyl-L-Cysteic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.