Description

2,6-Difluorophenol is a versatile fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of high-value pharmaceuticals, agrochemicals, and specialty materials. Industries such as pharmaceutical R&D, agrochemical manufacturing, and fine chemical production rely on its unique chemical structure to introduce fluorine atoms into complex molecules, thereby enhancing their biological activity, stability, and performance.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the difluorophenol moiety contributes to improved efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in high-performance displays (LCDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to enhance thermal stability, chemical resistance, and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a starting material for various fluorinated heterocycles and complex organic frameworks.
• Research & Development: Utilized in academic and industrial labs for method development and exploring new chemical entities in medicinal and material chemistry.

Basic Information

Product Name	2,6-Difluorophenol
CAS No.	28177-48-2
Molecular Formula	C6H4F2O
Molecular Weight	130.09 g/mol
Synonyms	2,6-Difluorophenol; 2,6-Difluoro-1-hydroxybenzene; 1-Hydroxy-2,6-difluorobenzene; Phenol, 2,6-difluoro-; 2,6-DFP; NSC 403120; AI3-28445; CCRIS 6665
EINECS	248-875-9

Quality Control

Our 2,6-Difluorophenol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clientele. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable, and our quality systems support compliance with major regulatory frameworks including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	34 - 38 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.