Description

4,6-Dimethyl-1H-Pyrimidine-2-Thione Hydrochloride is a versatile heterocyclic building block and key intermediate in organic synthesis. Its value lies in its functionalized pyrimidine-thione core, which is crucial for constructing complex molecules with potential biological activity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the pyrimidine scaffold is active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Acts as a versatile starting material for the preparation of more complex heterocyclic compounds through further functionalization reactions.
• Ligand in Coordination Chemistry: The thione and nitrogen atoms can act as donor sites for metal complexation, useful in catalysis or material science.
• Research & Development: Essential for academic and industrial R&D labs exploring new chemical entities and reaction pathways.

Basic Information

Product Name	4,6-Dimethyl-1H-Pyrimidine-2-Thione Hydrochloride
CAS No.	28176-16-1
Molecular Formula	C6H9N2S·HCl
Molecular Weight	176.67 g/mol
Synonyms	2-Mercapto-4,6-dimethylpyrimidine hydrochloride; 4,6-Dimethyl-2-pyrimidinethiol hydrochloride; 4,6-Dimethyl-2-mercaptopyrimidine hydrochloride; 2-Thio-4,6-dimethylpyrimidine hydrochloride; 4,6-Dimethylpyrimidine-2-thiol hydrochloride; NSC 403697; 1H-Pyrimidine-2-thione, 4,6-dimethyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4,6-Dimethyl-1H-Pyrimidine-2-Thione Hydrochloride is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or titration), identification (IR), and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC/Titration)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.