Description

3-(3-Pyridyl)Alanine is a non-proteinogenic amino acid derivative featuring a pyridine ring, making it a valuable chiral building block and intermediate in advanced organic synthesis. Its structural motif is critical for the development of novel pharmacologically active compounds and biochemical probes. This high-purity specialty chemical is essential for research and development in the pharmaceutical, agrochemical, and life science sectors, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neuroscience and metabolic disease research.
• Peptidomimetics & Drug Design: Used to incorporate pyridine functionality into peptide backbones, modifying stability, bioavailability, and receptor binding affinity.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, insecticides, and plant growth regulators with enhanced specificity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and as a building block for fluorescent or radioactive labeling probes.
• Ligand Synthesis for Catalysis: Useful for preparing novel pyridine-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A fundamental reagent for methodological development in organic chemistry and medicinal chemistry at universities and CROs.

Basic Information

Product Name	3-(3-Pyridyl)Alanine
CAS No.	28105-69-3
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	β-(3-Pyridyl)-L-alanine; 3-Pyridylalanine; (S)-2-Amino-3-(3-pyridyl)propanoic acid; L-3-(3-Pyridyl)alanine; 3-(3-Pyridinyl)alanine; 3-Pyridin-3-yl-alanine; 3-(Pyridin-3-yl)-L-alanine; H-3-Pal-OH
EINECS	Contact for details

Quality Control

We supply 3-(3-Pyridyl)Alanine in high-purity grades suitable for research and cGMP manufacturing. Every batch is subjected to rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure consistency and meet stringent customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the original container tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.