Description

D-Thyronine is a specific stereoisomer of the thyroid hormone thyronine, identified by the CAS registry number 28105-38-6. This compound is a critical chiral building block and reference standard in pharmaceutical research and development, particularly for studying thyroid hormone activity and metabolism. It is essential for researchers and manufacturers in the life sciences sector who require high-purity, well-characterized biochemical intermediates for drug discovery, analytical method development, and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method validation in drug development.
• Biochemical Research: Serves as a key chiral intermediate in the study of thyroid hormone biosynthesis, receptor binding, and metabolic pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed as a building block in the synthetic routes for novel thyroid hormone analogs and metabolic regulators.
• Diagnostic Reagent Development: Utilized in the formulation of calibration standards and reagents for clinical diagnostic assays related to thyroid function.
• Metabolite Studies: Acts as a standard for the identification and quantification of thyronine metabolites in biological samples during pharmacokinetic research.

Basic Information

Product Name	D-Thyronine
CAS No.	28105-38-6
Molecular Formula	C15H15NO4
Molecular Weight	273.29 g/mol
Synonyms	D-3,5,3',5'-Tetraiodothyronine; D-T4; Dextrothyroxine; D-Thyroxine; (R)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic Acid; 28105-38-6; D-Tetraiodothyronine
EINECS	Contact for details

Quality Control

Our D-Thyronine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile data is supplied with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; appropriate handling procedures should be followed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.