Description

H-Asp-Nh2 H2O is a high-purity, protected amino acid derivative, specifically the monohydrate form of L-Aspartic acid β-amide. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, offering precise control over molecular structure. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for peptide synthesis and active pharmaceutical ingredient (API) development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex peptides, peptidomimetics, and novel therapeutic agents.
• Bioconjugation & Linker Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Protecting Group Strategy: The amide group provides a protected form of aspartic acid for selective reactions in multi-step synthetic routes.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor in metabolic pathway research.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, flavors, and fragrances requiring specific chirality.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and biomaterials.

Basic Information

Product Name	H-Asp-Nh2 H2O
CAS No.	28057-52-5
Molecular Formula	C4H8N2O3 • H2O
Molecular Weight	150.13 g/mol (Anhydrous basis: 132.12 g/mol)
Synonyms	L-Aspartic acid β-amide monohydrate; H-Asp-NH2•H2O; (S)-2-Aminosuccinamic acid monohydrate; Aspartic acid amide monohydrate; β-Asparagine; L-Asparagine analog; 2-Aminosuccinamide monohydrate; L-2-Aminosuccinamic acid monohydrate
EINECS	Contact for details

Quality Control

Our H-Asp-Nh2 H2O is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	Specific range provided on COA
Water Content (KF)	Theoretical or ≤12.0%
Heavy Metals	<10 ppm
Residue on Ignition	<0.1%
Related Substances (HPLC)	Individual impurity <0.5%; Total impurities <2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.