Description

Dl-Cyclobutylglycine is a non-proteinogenic amino acid derivative featuring a cyclobutyl side chain, offering unique steric and conformational properties. This compound is a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as peptide mimetics and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptidomimetics & Constrained Peptides: Used to introduce conformational rigidity into peptide backbones, enhancing metabolic stability and biological activity.
• Agrochemical Research: Serves as a building block for synthesizing novel compounds with potential herbicidal or insecticidal activity.
• Chemical Biology & Proteomics: Employed as a tool compound or labeled analog for studying enzyme mechanisms and protein interactions.
• Ligand & Catalyst Development: Useful in the design of novel chiral ligands for asymmetric catalysis and metal complexes.
• Academic & Institutional Research: A fundamental reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Dl-Cyclobutylglycine
CAS No.	28024-69-3
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	DL-2-Amino-2-cyclobutylacetic Acid; (±)-2-Amino-2-cyclobutylacetic Acid; Cyclobutylglycine; DL-Cyclobutylglycine; rac-Cyclobutylglycine; 2-Cyclobutylglycine; (RS)-2-Amino-2-cyclobutylacetic Acid; Amino(cyclobutyl)acetic Acid
EINECS	Contact for details

Quality Control

Our Dl-Cyclobutylglycine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Racemic mixture (DL)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.