Description

Neomycin B Sulphate is a water-soluble aminoglycoside antibiotic salt, specifically the sulfate salt of the Neomycin B component. This compound is valued for its potent broad-spectrum antibacterial activity, particularly against Gram-negative bacteria. It is a critical raw material and intermediate in the pharmaceutical industry for the formulation of topical medications, veterinary products, and in specific research applications. The product is supplied as a high-purity material suitable for demanding manufacturing processes.

Application

• Pharmaceutical Active Ingredient: Key component in the manufacture of topical antibiotic ointments, creams, and eye/ear drops.
• Veterinary Medicine: Used in formulations for treating bacterial infections in livestock and companion animals.
• Research & Development: Serves as a standard or reference compound in microbiological studies and antibiotic mechanism research.
• Cell Culture Applications: Employed in selective media to prevent bacterial contamination in laboratory cell cultures.
• API Intermediate: Acts as a starting material or intermediate in the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Neomycin B Sulphate
CAS No.	28002-70-2
Molecular Formula	C₂₃H₄₆N₆O₁₃ · H₂SO₄
Molecular Weight	908.9 g/mol (for Neomycin B Sulfate)
Synonyms	Neomycin B Sulfate; Framycetin Sulfate; Neomycin B, sulfate; Neomycin B Sulphate; Neomycin B, sulphuric acid salt; 2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]-D-streptamine sulfate; Antibiotic FRM 2 sulfate
EINECS	Contact for details

Quality Control

Our Neomycin B Sulphate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. Specifications typically align with pharmacopeial guidelines (e.g., USP, EP) where applicable. A detailed Certificate of Analysis (COA) documenting identity, purity, potency, and related substances is provided with every shipment to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
pH (1% Solution)	5.0 - 7.5
Water (Karl Fischer)	≤ 8.0 %
Residue on Ignition	≤ 1.0 %
Related Substances (HPLC)	Individual impurity ≤ 2.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.