Description

4-Methyl-6-Phenyl-Pyrimidine-2-Thiol is a versatile heterocyclic building block featuring a pyrimidine core substituted with a phenyl group and a thiol moiety. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in charge-transport layers.
• Chemical Synthesis: Employed in organic synthesis for the construction of complex fused-ring systems and as a source of the thiol functional group for further derivatization.
• Ligand & Catalyst Development: Utilized in coordination chemistry to create novel ligands for catalytic applications or metal ion sensing.

Basic Information

Product Name	4-Methyl-6-Phenyl-Pyrimidine-2-Thiol
CAS No.	27955-44-8
Molecular Formula	C11H10N2S
Molecular Weight	202.27 g/mol
Synonyms	6-Phenyl-4-methylpyrimidine-2-thiol; 4-Methyl-6-phenyl-2-pyrimidinethiol; 4-Methyl-6-phenyl-2-mercaptopyrimidine; 2-Mercapto-4-methyl-6-phenylpyrimidine; 2-Pyrimidinethiol, 4-methyl-6-phenyl-; 4-Methyl-6-phenylpyrimidine-2-thione; 4-Methyl-6-phenyl-2(1H)-pyrimidinethione
EINECS	Contact for details

Quality Control

Our 4-Methyl-6-Phenyl-Pyrimidine-2-Thiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening a new container to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.