Description

Boc-L-Leu-L-Leu-Gly-Ome CAS NO 27545-11-5 is a protected tripeptide derivative, specifically a methyl ester of a leucine-leucine-glycine sequence with a tert-butyloxycarbonyl (Boc) protecting group on the N-terminus. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins for research and development. It is primarily utilized by pharmaceutical researchers, biochemists, and fine chemical manufacturers working on peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential construction of longer peptide chains in automated synthesizers.
• Pharmaceutical Research: Serves as a building block for developing novel peptide drugs targeting various diseases.
• Biochemical Research: Used in the study of protein-protein interactions, enzyme substrates, and signal transduction pathways.
• Production of Custom Peptides: Essential raw material for CROs and CDMOs offering bespoke peptide synthesis services.
• Proteomics and Biomarker Discovery: Can be incorporated into synthetic peptide standards for mass spectrometry calibration.
• Antibiotic Research: Useful in synthesizing analogs of natural antimicrobial peptides.

Basic Information

Product Name	Boc-L-Leu-L-Leu-Gly-Ome
CAS No.	27545-11-5
Molecular Formula	C20H37N3O6
Molecular Weight	415.53 g/mol
Synonyms	Boc-Leu-Leu-Gly-OMe; (tert-Butoxycarbonyl)-L-leucyl-L-leucylglycine methyl ester; N-(tert-Butoxycarbonyl)-L-leucyl-L-leucylglycine methyl ester; Boc-LLG-OMe; Methyl N-[(2S)-1-[[(2S)-1-[(2-tert-butoxy-2-oxoethoxy)amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]glycinate; N-Boc-L-leucyl-L-leucylglycine methyl ester; Boc-L-Leu-L-Leu-Gly methyl ester
EINECS	Contact for details

Quality Control

Our Boc-L-Leu-L-Leu-Gly-Ome is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing purity, chiral integrity, and solvent residues are available for every shipment. We support research and production needs with material traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant after each use to prevent degradation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.