Description

2-(Chloromethyl)-2-Methyl-1,2,3,4-Tetrahydroquinazolin-4-One is a versatile and high-value heterocyclic building block with a fused quinazolinone core. This compound is critical for advanced organic synthesis, serving as a key intermediate in the development of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and libraries for screening.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic or photonic properties.
• Chemical Reference Standard: Supplied to analytical laboratories for use as a high-purity standard in method development and quality control testing.

Basic Information

Product Name	2-(Chloromethyl)-2-Methyl-1,2,3,4-Tetrahydroquinazolin-4-One
CAS No.	27545-02-4
Molecular Formula	C₁₀H₁₁ClN₂O
Molecular Weight	210.66 g/mol
Synonyms	2-(Chloromethyl)-2-methyl-1,2,3,4-tetrahydro-4-quinazolinone; 2-Methyl-2-(chloromethyl)-1,2,3,4-tetrahydroquinazolin-4-one; 4(1H)-Quinazolinone, 2-(chloromethyl)-1,2,3,4-tetrahydro-2-methyl-; Tetrahydroquinazolinone derivative; Quinazolin-4-one intermediate
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-2-Methyl-1,2,3,4-Tetrahydroquinazolin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.