Description

Ac-Cys(Trt)-OH is a protected cysteine derivative, specifically N-acetyl-S-trityl-L-cysteine, widely used as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers who require precise control over cysteine reactivity and disulfide bond formation during complex peptide assembly. It is primarily utilized by the pharmaceutical, biotechnology, and research sectors for developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of cysteine residues, protecting the thiol group from unwanted side reactions.
• Therapeutic Peptide Production: Used in the synthesis of peptides with disulfide bridges, which are critical for the structural stability and biological activity of many hormone and drug candidates.
• Research & Development: Serves as a standard reagent in academic and industrial R&D labs for studying protein folding, peptide structure-activity relationships, and novel synthetic methodologies.
• Bioconjugation Chemistry: Acts as a precursor for creating peptide-based conjugates for targeted drug delivery, imaging probes, and antibody-drug conjugates (ADCs).
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	Ac-Cys(Trt)-OH
CAS No.	27486-87-9
Molecular Formula	C24H23NO3S
Molecular Weight	405.51 g/mol
Synonyms	N-Acetyl-S-trityl-L-cysteine; N-Acetyl-S-tritylcysteine; Ac-Cys(Trt)-OH; L-Cysteine, N-acetyl-, S-trityl derivative; N-Acetyl-S-(triphenylmethyl)-L-cysteine; N-Acetyl-S-trityl-L-cysteine; N-Acetyl-S-tritylcysteine; Ac-Cys(Trt)
EINECS	Contact for details

Quality Control

Our Ac-Cys(Trt)-OH is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.