Description

H-Ala-Ala-Tyr-Ala-Oh is a synthetic tetrapeptide sequence consisting of alanine and tyrosine residues. This compound is a valuable building block in peptide synthesis and biochemical research, offering a defined structure for studying enzyme-substrate interactions and protein folding. It is primarily utilized by research institutions and pharmaceutical developers focused on proteomics, enzyme kinetics, and the development of novel therapeutic peptides.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic assays, particularly for studying proteases like chymotrypsin which cleave at tyrosine residues.
• Pharmaceutical Development: Serves as a key intermediate or model compound in the research and development of peptide-based drugs and diagnostic agents.
• Proteomics & Peptide Mapping: Acts as a reference peptide in mass spectrometry for calibration and in studies of peptide fragmentation patterns.
• Enzyme Kinetics Studies: Employed to investigate catalytic mechanisms, inhibition, and specificity of various peptidases and proteolytic enzymes.
• Academic Research: Utilized in university and institutional labs for teaching and fundamental research in biochemistry, medicinal chemistry, and molecular biology.
• Custom Peptide Synthesis: Incorporated as a specific sequence segment in the custom synthesis of longer, more complex peptides for specialized applications.

Basic Information

Product Name	H-Ala-Ala-Tyr-Ala-Oh
CAS No.	27485-58-1
Molecular Formula	C19H27N5O6
Molecular Weight	421.45 g/mol
Synonyms	Ala-Ala-Tyr-Ala; AAYA; H-Ala-Ala-Tyr-Ala-OH; Tetrapeptide AAYA; L-Alanyl-L-alanyl-L-tyrosyl-L-alanine; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoic acid; Ala-Ala-Tyr-Ala-OH
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Tyr-Ala-Oh is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee consistent quality and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be kept under desiccated conditions. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.