Description

3-[1-(Hydroxymethyl)Ethyl]Cyclo[D-Lac-L-Pro-L-Ile-n-Methyl-L-Val-n-Methyl-L-Ala-βala-] is a complex, synthetic cyclic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its unique structural framework, which serves as a sophisticated scaffold for modulating biological activity and improving pharmacokinetic properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in oncology, immunology, and metabolic disease research. Its precise stereochemistry and cyclic nature make it a critical intermediate for probing peptide-protein interactions and developing next-generation bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel peptide-based drug candidates and prodrugs.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Protease Inhibitor Development: Investigated for its potential in creating inhibitors for specific enzymatic targets due to its constrained cyclic structure.
• Chemical Biology Probes: Employed in the development of molecular probes to study cellular signaling pathways and protein functions.
• Peptidomimetic Design: Acts as a core structure for designing peptidomimetics with enhanced metabolic stability and membrane permeability.
• High-Value API Synthesis: Utilized in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.

Basic Information

Product Name	3-[1-(Hydroxymethyl)Ethyl]Cyclo[D-Lac-L-Pro-L-Ile-n-Methyl-L-Val-n-Methyl-L-Ala-βala-]
CAS No.	27482-49-1
Molecular Formula	C36H62N6O9
Molecular Weight	710.91 g/mol
Synonyms	Cyclo(D-lactoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl-N-methyl-L-alanyl-β-alanyl-3-(1-hydroxyethyl)); 3-(1-Hydroxyethyl)-cyclo(D-Lac-L-Pro-L-Ile-N-Me-L-Val-N-Me-L-Ala-β-Ala); Cyclic Hexapeptide Derivative [D-Lac-L-Pro-L-Ile-N-Me-L-Val-N-Me-L-Ala-β-Ala]; Cyclo[D-Lac-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-β-Ala] 3-(1-Hydroxyethyl) Derivative; CAS 27482-49-1; Complex Cyclic Peptidomimetic
EINECS	Contact for details

Quality Control

Every batch of 3-[1-(Hydroxymethyl)Ethyl]Cyclo[D-Lac-L-Pro-L-Ile-n-Methyl-L-Val-n-Methyl-L-Ala-βala-] is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.