Description

Glutamic Acid-Lysine-Alanine Polymer CAS NO 27456-63-9 is a synthetic polypeptide composed of the amino acids glutamic acid, lysine, and alanine. This engineered polymer is valued for its unique polyampholyte structure, offering tunable charge characteristics and biocompatibility. It is primarily utilized in advanced biomedical research, pharmaceutical development, and specialized material science applications.

Application

• Biomedical Research: Used as a model polyampholyte for studying protein interactions, cell adhesion, and biomimetic materials.
• Drug Delivery Systems: Serves as a functional carrier or coating material for controlled release formulations due to its modifiable surface charge.
• Tissue Engineering Scaffolds: Incorporated into hydrogels or matrices to provide specific biochemical cues for cell growth and differentiation.
• Cosmetic & Personal Care: Functions as a film-forming agent, moisturizer, or conditioning polymer in high-performance skincare and haircare products.
• Biocompatible Coatings: Applied to medical devices or implants to enhance surface biocompatibility and reduce non-specific protein adsorption.
• Enzyme Immobilization: Acts as a support matrix for immobilizing enzymes in biocatalytic processes.

Basic Information

Product Name	Glutamic Acid-Lysine-Alanine Polymer
CAS No.	27456-63-9
Molecular Formula	(C5H9NO4·C6H14N2O2·C3H7NO2)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(Glu-Lys-Ala); GLA Polymer; Poly(glutamic acid-lysine-alanine); Glutamic Acid/Lysine/Alanine Copolymer; EKA Polymer; Poly(E-K-A); Poly(γ-glutamyl-lysyl-alanyl); Amino Acid Terpolymer
EINECS	Contact for details

Quality Control

Our Glutamic Acid-Lysine-Alanine Polymer is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure consistency in molecular weight distribution, amino acid composition, and purity. Certificates of Analysis (COA) detailing specifications such as HPLC purity, endotoxin levels, and residual solvent content are provided with every shipment to support your R&D and cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture uptake, which may affect properties.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Amino Acid Analysis)	≥ 95.0% (by molar ratio)
Purity (HPLC)	≥ 90.0% (Polymer Peak)
Molecular Weight (GPC)	Specified range available (e.g., 5kDa - 50kDa)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Endotoxin (LAL)	< 10.0 EU/mg (for biomedical grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.