Description

3-Bromo-4-Fluorophenol is a halogenated phenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules with halogenated aromatic cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro groups enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed as a monomer or functionalization agent to introduce halogenated phenolic groups into polymer chains, altering thermal and chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	3-Bromo-4-Fluorophenol
CAS No.	27407-11-0
Molecular Formula	C6H4BrFO
Molecular Weight	191.00 g/mol
Synonyms	4-Fluoro-3-bromophenol; 3-Bromo-4-fluorophenol; Phenol, 3-bromo-4-fluoro-; 3-Brom-4-fluorphenol (German); 3-Bromo-4-fluoro-1-hydroxybenzene; 1-Bromo-2-fluoro-4-hydroxybenzene; 2-Fluoro-5-bromophenol
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluorophenol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.