Description

5-Brom-6-Cyclopropyl-4-Chlorpyrimidine is a high-purity halogenated pyrimidine building block, a critical intermediate in modern synthetic organic chemistry. Its value lies in its versatile reactivity, enabling the construction of complex molecular architectures for advanced research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine core.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring specific halogenated pyrimidine motifs.

Basic Information

Product Name	5-Brom-6-Cyclopropyl-4-Chlorpyrimidine
CAS No.	27192-21-8
Molecular Formula	C7H6BrClN2
Molecular Weight	233.49 g/mol
Synonyms	4-Chloro-5-bromo-6-cyclopropylpyrimidine; 5-Bromo-4-chloro-6-cyclopropylpyrimidine; 6-Cyclopropyl-5-bromo-4-chloropyrimidine; 27192-21-8; 4-Chloro-6-cyclopropyl-5-bromopyrimidine; 5-Bromo-6-cyclopropyl-4-chloropyrimidine; 5-Bromo-4-chloro-6-cyclopropyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Brom-6-Cyclopropyl-4-Chlorpyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.