Description

trans-Oxazolam is a high-purity benzodiazepine derivative of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs) targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of anxiolytic and sedative-hypnotic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced benzodiazepine-based therapeutic agents.
• Research & Development: Used in preclinical and clinical research for studying GABA-A receptor modulation and related neurological pathways.
• Reference Standard: Serves as an analytical standard for quality control and method validation in pharmaceutical laboratories.
• Chemical Synthesis: Employed in organic synthesis for creating novel chemical entities with potential pharmacological activity.
• Academic Studies: Utilized in university and institutional research for medicinal chemistry and pharmacology programs.

Basic Information

Product Name	trans-Oxazolam
CAS No.	27167-30-2
Molecular Formula	C₁₈H₁₇ClN₂O₂
Molecular Weight	328.79 g/mol
Synonyms	10-Chloro-2,3,7,11b-tetrahydro-2-methyl-11b-phenyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one; Oxazolam (trans-isomer); 27167-30-2; trans-10-Chloro-2-methyl-11b-phenyl-2,3,5,6,7,11b-hexahydrooxazolo[3,2-d][1,4]benzodiazepin-6-one; Serenal (trans-isomer); CS-300; Oxazolam trans form
EINECS	Contact for details

Quality Control

Our trans-Oxazolam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, IR for identification, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.