Description

Dacuronium Bromide CAS NO 27115-86-2 is a quaternary ammonium neuromuscular blocking agent primarily used in clinical and research settings. This compound is critical for inducing skeletal muscle relaxation during surgical procedures and anesthesia. It is an essential reagent for pharmaceutical manufacturers, research laboratories, and academic institutions focused on anesthesiology, pharmacology, and neuromuscular physiology.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of advanced neuromuscular blocking agents and related pharmaceutical actives.
• Clinical Anesthesia: Used as a non-depolarizing muscle relaxant to facilitate endotracheal intubation and provide skeletal muscle relaxation during surgery.
• Biomedical Research: A vital tool for studying neuromuscular junction physiology, receptor pharmacology, and the mechanisms of muscle contraction and relaxation.
• Pharmacology Studies: Employed in in vitro and in vivo assays to evaluate the potency, duration, and reversibility of neuromuscular blockade.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Veterinary Medicine: Applied in veterinary surgical procedures requiring controlled muscle paralysis.

Basic Information

Product Name	Dacuronium Bromide
CAS No.	27115-86-2
Molecular Formula	C40H60Br2N2O4
Molecular Weight	780.73 g/mol
Synonyms	Dacuronium Bromide; Dacuronium Dibromide; 1,1'-[3α,17β-Bis(acetyloxy)-5α-androstane-2β,16β-diyl]bis(1-methylpiperidinium) Dibromide; 2β,16β-Bis(1-methylpiperidinio)-3α,17β-diacetoxy-5α-androstane Dibromide; Pipecuronium Bromide Impurity; Neuromuscular Blocking Agent; Norcuronium Bromide (related)
EINECS	Contact for details

Quality Control

Our Dacuronium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other pharmacopeial methods, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.