Description

H-D-Glu(Ome)-Ome Hcl is a protected derivative of D-glutamic acid, specifically the dimethyl ester hydrochloride salt. This compound is a crucial chiral building block and intermediate in the synthesis of complex peptides and pharmaceutical active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of peptide-based drugs and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-glutamic acid residues with protected side chains.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies and enzyme-substrate interaction research.
• Prodrug Development: Utilized in designing prodrugs where the ester groups allow for controlled release or improved bioavailability.
• Fine Chemical Synthesis: Intermediate for creating specialized compounds in agrochemical and material science research.

Basic Information

Item	Detail
Product Name	H-D-Glu(Ome)-Ome Hcl
CAS No.	27025-25-8
Molecular Formula	C7H14ClNO4
Molecular Weight	211.65 g/mol
Synonyms	D-Glutamic Acid Dimethyl Ester Hydrochloride; H-D-Glu(OMe)-OMe·HCl; (R)-2-Amino-1,5-dimethoxy-1,5-dioxopentan-2-aminium chloride; Dimethyl D-glutamate hydrochloride; D-Glutamic acid dimethyl ester HCl; D-Glu(OMe)-OMe·HCl; (2R)-2-Aminopentanedioic acid 1,5-dimethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our H-D-Glu(Ome)-Ome Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.