Description

1-Methyl-Dl-Tryptophan is a synthetic derivative of the essential amino acid tryptophan, featuring a methyl group substitution on the indole nitrogen. This modification makes it a valuable biochemical tool and a key intermediate in pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in metabolic pathway studies, enzyme inhibition research, and the synthesis of more complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard, inhibitor, or substrate in enzymatic studies, particularly those involving tryptophan metabolism and indoleamine 2,3-dioxygenase (IDO) pathways.
• Metabolic Studies: Employed in laboratory research to investigate amino acid metabolism, protein synthesis, and related biochemical processes.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical and life science laboratories.
• Peptide Synthesis: Can be incorporated into synthetic peptides for structure-activity relationship (SAR) studies and the development of peptide-based therapeutics.

Basic Information

Product Name	1-Methyl-Dl-Tryptophan
CAS No.	26988-72-7
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	1-Methyl-DL-tryptophan; 1-Methyltryptophan; DL-1-Methyltryptophan; (±)-1-Methyltryptophan; 1-MT; NSC 721782; (RS)-1-Methyltryptophan; α-Methyl-DL-tryptophan; 1-Methyl-1H-indole-3-alanine
EINECS	Contact for details

Quality Control

Our 1-Methyl-Dl-Tryptophan is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.