Description

(4-Fluorophenylamino)Methylenemalonic Acid Diethyl Ester is a versatile and high-purity chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the fine chemical industry for creating active pharmaceutical ingredients (APIs) and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the fluorophenyl moiety for enhanced biological activity.
• Organic Synthesis Building Block: Serves as a versatile reagent in Knoevenagel condensation and other C-C bond-forming reactions to construct complex molecular architectures.
• Material Science Research: Employed in the development of specialty polymers and functional materials where the introduction of fluorine atoms is desired for specific properties.
• Academic & Industrial R&D: A valuable compound for methodological studies and scale-up process development in synthetic chemistry laboratories.

Basic Information

Product Name	(4-Fluorophenylamino)Methylenemalonic Acid Diethyl Ester
CAS No.	26832-96-2
Molecular Formula	C14H16FNO4
Molecular Weight	281.28 g/mol
Synonyms	Diethyl (4-Fluorophenylamino)methylene malonate; Diethyl [(4-Fluorophenyl)amino]methylenemalonate; (4-Fluorophenylamino)methylene-propanedioic Acid Diethyl Ester; Propanedioic acid, [(4-fluorophenyl)amino]methylene-, diethyl ester; Ethyl (4-Fluorophenylamino)methylenemalonate; 2-[(4-Fluorophenyl)amino]methylenemalonic Acid Diethyl Ester; Diethyl (4-Fluoroanilino)methylenemalonate
EINECS	Contact for details

Quality Control

Our (4-Fluorophenylamino)Methylenemalonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.