Description

Poly-L-Arginine Sulfate Salt is a high-purity, water-soluble polyamino acid derivative of the essential amino acid L-arginine. This compound is valued for its strong cationic nature and biocompatibility, making it a critical functional polymer in advanced life science and pharmaceutical applications. It is primarily utilized by researchers and manufacturers in the biotech, pharmaceutical, and cosmetic industries for its unique macromolecular properties.

Application

• Biomaterial & Drug Delivery: As a cationic polymer for constructing polyelectrolyte multilayers, gene delivery vectors (polyplexes), and controlled-release systems.
• Cell Culture & Tissue Engineering: Coating agent for cell culture surfaces to promote cell adhesion and proliferation, particularly for sensitive cell lines.
• Cosmetic Formulations: Active ingredient in skincare products for its purported moisturizing and anti-aging properties, often used in serums and creams.
• Enzyme Immobilization & Stabilization: Substrate for immobilizing enzymes and proteins due to its positive charge and macromolecular structure.
• Pharmaceutical Intermediates: Used in the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs).
• Research Reagent: Essential tool in biochemical and biophysical research for studying protein-polymer interactions, membrane permeability, and nucleic acid complexation.

Basic Information

Product Name	Poly-L-Arginine Sulfate Salt
CAS No.	26700-68-5
Molecular Formula	(C6H14N4O2 • H2SO4)n
Molecular Weight	~ 5,000 - 70,000 Da (varies by grade)
Synonyms	Poly(arginine) sulfate; Poly-L-arginine hydrogensulfate; PArg; Polyarginine sulfate salt; L-Arginine homopolymer sulfate; P-L-Arg; (Arg)n sulfate; Poly(α-L-arginine) sulfate
EINECS	Contact for details

Quality Control

Our Poly-L-Arginine Sulfate Salt is produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) that include data on molecular weight distribution, purity, and endotoxin levels where applicable. Our quality commitment aligns with the standards required for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent moisture uptake, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white powder or fibrous solid
Identification (IR)	Conforms to reference spectrum
Assay (Nitrogen Content)	≥ 95.0% (on anhydrous basis)
Molecular Weight (GPC)	Specified range (e.g., 15,000 - 70,000 Da)
Water Content (KF)	≤ 5.0 %
pH (1% solution)	5.0 - 7.0
Endotoxin (LAL)	< 0.1 EU/mg (for specific grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.